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Unraveling the Principles of the Epigenome Evolution

Utilizing Human, rodent and pig cells, key epigenetic markers are compared to understand how this epignomic system evolved. “Comparative epigenomics reveals regulatory features of the genome that cannot be discerned from sequence comparisons alone.” Read more about it: Comparative Epigenomic Annotation of Regulatory DNA .
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Chimeric Pigs Produced from Induced Pluripotent Stem Cells Demonstrate Germline Transmission and No Evidence of Tumor Formation in Young Pigs

Read our landmark paper “Chimeric Pigs Produced from Induced Pluripotent Stem Cells Demonstrate Germline Transmission and No Evidence of Tumor Formation in Young Pigs” published in the journal Stem Cells- one of the leading stem cell journals in the world. This article highlights how stringent analysis of chimeric pigs at…
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We made the cover of Stem Cells and Development!

  Porcine induced pluripotent stem cells produce chimeric offspring. West FD, Terlouw SL, Kwon DJ, Mumaw JL, Dhara SK, Hasneen K, Dobrinsky JR, Stice SL. Stem Cells Dev. 2010 Aug;19(8):1211-20.   Abstract Ethical and moral issues rule out the use of human induced pluripotent stem cells (iPSCs) in chimera studies…
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